Bio

Dr. Dipak K. Giri is a board-certified veterinary pathologist and an expert in diagnostic and investigative pathology with years of experience and training in academia and industry. Dr. Giri completed his residency in Veterinary Anatomic Pathology from the University of Georgia and board-certified by the American College of Veterinary Pathologists. He served in various capacities as pathologist and /or investigator in a few institutes including Texas A&M University and Baylor College of Medicine. Dr. Giri has special interest in neoplastic diseases. He has published more than 50 scientific papers in peer-reviewed journals and presented scientific findings in professional meetings and conferences. Dr. Giri’s professional affiliations include American College of Veterinary Pathologists, State Board of Veterinary Medicine, Georgia, USA, State Board of Veterinary Medicine, Texas, USA, Society of Toxicologic Pathology, CL Davies Foundation, Texas Veterinary Medical Association.

Publications:

Diagnostic pathology:

Dipak K. Giri*, F. Alosio , D. K. Ajithdoss, , H. E. Hein, A. Ambrus, J. A. Lidbury and B.F. Porter (2011): Giant cell Glioblastoma in the cerebral hemisphere of a Pembroke Welsh Corgi. J. Comparative Pathology 144(4):324-7.

Dipak K. Giri, E. Quist, A. Ambrus, B. Porter, G. Bratton, R. Storts (2010): Neuronal intestinal dysplasia with fatal bacterial colitis in a foal. Veterinary Pathology 47 (4): 654-657.

Dipak K. Giri, Will Sims, Radhakrishna Sura, Jocelyn Cooper, Boris K Gavrilov, Joanne Mansell (2010): Cerebral and renal phaeohyphomycosis in a dog infected with Bipolaris species. Veterinary Pathology 48(3):754 -7

E.M. Quist, C. Belcher, G. Levine, M. Johnson, J.J. Heatley, M. Kiupel and D.K. Giri (2011): A case of dissemi1ated histoplasmosis with concurrent oral candidiasis in an Eclectus parrot (Eclectus raretus). Avian Pathology 40(2):207-11.

Dipak K. Giri, Debra L. Miller, Larry J. Thompson, Lesley Mailler, Eloise Styer, and Charles Baldwin (2007): Superoxide dismutase expression and oxidative damage in a case of myopathy in brown pelicans (Pelecanus occidentalis). J. Veterinary Diagnostic and Investigation 19: 301-304.

Dipak K. Giri and Ittmann, M. (1999): Inactivation of the PTEN tumor suppressor gene is associated with increased angiogenesis in clinically localized prostate carcinoma. Human Pathology 30: 419-424.

Murray E. Hines II, Shane Stiver , Dipak K. Giri , Lisa Whittington, Cindy Watson, Jill Johnson , Julie Musgrove , Mel Pence, David Hurley , Charles Baldwin , Ian A. Gardner , Sharif Aly (2007): Efficacy of spheroplastic and cell-wall competent vaccines for Mycobacterium avium subsp. paratuberculosis in experimentally-challenged baby goats. Veterinary Microbiology 120: 261–283.

Investigative pathology:

Cortez MA, Ivan C, Valdecanas D, Wang X, Peltier HJ, Ye Y,1 Araujo L, Carbone DP, Shilo K, Giri DK, Kelnar K, Martin D, Komaki R, Gomez DR, Krishnan S, Calin GA, Bader AG, Welsh JW (2016): PDL1 regulation by p53 via miR-34. J.Natl. Cancer Inst. 108 (1): djv303

Cortez MA, Valdecanas D, Zhang X, Zhan Y, Bhardwaj V, Calin GA, Komaki R, Giri DK, Quini CC, Wolfe T, Peltier HJ, Bader AG, Heymach JV, Meyn RE, Welsh JW. (2014): Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer. Molecular Therapy (8): 1494-503.

Klaus W. Wagner, Shilpa Dhar,*, Uma Giri,* Yong Kun Wei, Dipak Giri, Na Li, Tina Cascone, Jae-Hwan Kim, Baruch Erez, Yuanqing Ye, Babita Saigal, Xifeng Wu, Mien-Chie Hung, John Heymach, Min Gyu Lee (2013): KDM2A is an epigenetic modifier regulating oncogenic capabilities in lung cancer. J Clinical. Investigation. 123(12): 5231-46.

Murray E. Hines II, Shane Stiver , Dipak K. Giri , Lisa Whittington, Cindy Watson, Jill Johnson , Julie Musgrove , Mel Pence, David Hurley , Charles Baldwin , Ian A. Gardner , Sharif Aly (2007): Efficacy of spheroplastic and cell-wall competent vaccines for Mycobacterium avium subsp. paratuberculosis in experimentally-challenged baby goats. Veterinary Microbiology 120: 261–283.

Dipak K. Giri, Mohamed Ali Seyed*, Long-Yuan Li*, Dung Fang Lee, Ling Pin, Geoffrey Bartholomeusz, Wang, S C and Mien-Chie Hung. (2005): Endosomal transport of HER2: A mechanism for nuclear entry of cell surface receptor. Molecular and Cellular Biology 25, 11005-11018. (*equally contributed).

Wang, S-C., Lien, H-C., Xia, W., Chen, I-F., Lo, H-W., Wang, Z., Ali-Seyed, M.,Bartholomeusz, G., Ou-Yang, F., Dipak K. Giri and Hung, M-C (2004):

Binding at and transactivation of COX-2 promoter by nuclear tyrosine kinase receptor ErbB2. Cancer Cell 6:251-261.

Kwabi-Ado, B, Dipak K. Giri, Smidth, K, Podsypanina, K, Parsons, R, Greengerg, N,Ittmann,M.(2001): Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression. Proceedings of National Academy of Sciences (USA) 98, 11563-11568.

Dipak K. Giri, Ozen, M and Ittmann,M (2001): Interleukin-6 is an autocrine growth factor in human prostate cancer. American J. Pathology 159, 2159-2165.

Dipak K. Giri, and Ittmann,M (2001): Interleukin-8 is a paracrine inducer of fibroblast Growth Factor 2, a stromal and epithelial growth factor in benign prostatic hyperplasia. American J. Pathology 159, 139-147.

Ozen, M , Dipak K. Giri, , Frederic R, Mansukhani, A and Ittmann,M (2001): Role of Fibroblast growth Factor Signaling in prostate cancer cell survival. Journal of National Cancer Institute 93, 1783-90.

Dipak K. Giri and Ittmann, M (2000): IL-1 alpha is a paracrine inducer of FGF-7, a key epithelial growth factor in benign prostatic hyperplasia. American J. Pathology 157, 249-255.

Frederic R, Dipak K. Giri, Bernard K A, Mansukhani, A and Ittmann,M (2000): Increased expression of fibroblast growth factor 6 in human prostatic intraepithelial neoplasia and prostate cancer. Cancer Research 60, 4245-50

Dipak K. Giri, Mehta, R.T.,Kansal, R.and Aggarwal, B.B.(1998): Mycobacterium avium activates nuclear transcription factor-kB in different cell types through reactive oxygen intermediates. J. Immunology 161 (9): 4834-41.